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These may be life threatening in some cases, although afebrile skin reactions are not always minor (eg, urticaria and angioedema). Institution of care at a young age impacts long-term survival; hence, timing of diagnosis and recognition of signs and symptoms are crucial. In adults, calcium chloride 10% can be diluted in 100 mL normal saline and infused over 5 minutes through a central venous line. Readers are encouraged to consult other references to better understand the intricacies of the neurologic examination. EMs, but not PMs, hemodynamic responses to metoprolol (a CYP2D6 substrate) were pronounced and prolonged during concomitant diphenhydramine administration. Other causes include foods (likely the most significant offenders) and physical factors such as cold or pressure, infections, and exposure to latex. The results of this trial support the use of temsirolimus for first-line treatment of high risk patients with poor prognostic features, making it the first therapy specifically approved for this patient population. Atherosclerosis of the extracranial arteries, a frequent cause of stroke, can be evaluated using ultrasonography (referred to as duplex sonography, carotid Doppler, or color-flow Doppler), magnetic resonance angiography (MRA), or computed tomographic angiography (CTA). Women who plan to travel during the third trimester should assess available medical facilities at the destination in anticipation of potential complications or early delivery. The CDC has resources that provide guidance on medical management of chemical hazards (, emergency healthcare preparedness (, and access to the Strategic National Stockpile ( among other areas of interest. Poisoning can occur from a variety of circumstances such as the unintentional ingestion of medicines by young children. Interestingly, a study has shown that a therapeutic serum concentration of theophylline can be achieved for control of apnea in premature infants less than 30 weeks' gestation after topical application of gel containing a standard dose of theophylline. Clinical studies suggest that achieving a free-fraction (unbound) area-under-the-curve to MIC ratio (fAUC/MIC) of greater than or equal to 211 or AUC/MIC (total) of greater than 400 improved outcomes of patients with S. During radionuclide ventriculography, Tc-pertechnate is introduced into the blood stream and imaged as it circulates through the heart. After binding, antibodies are induced that destroy the cell.